TUNING FERULIC ACID SOLUBILITY IN CHOLINE-CHLORIDE- AND BETAINE-BASED DEEP EUTECTIC SOLVENTS: EXPERIMENTAL DETERMINATION AND MACHINE LEARNING MODELING

Tuning Ferulic Acid Solubility in Choline-Chloride- and Betaine-Based Deep Eutectic Solvents: Experimental Determination and Machine Learning Modeling

Deep eutectic solvents (DES) represent a promising class of green solvents, offering particular utility in the extraction and development of new formulations of natural compounds such as ferulic acid (FA).The experimental phase of the study undertook a systematic investigation of the solubility of FA in DES, comprising choline chloride or betaine a

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Aortic stenosis: From diagnosis to optimal treatment

Aortic stenosis is the most frequent valvular heart disease.Aortic sclerosis is the first characteristic lesion of the cusps, which is considered Chicken Rotisserie Element today as the process similar to atherosclerosis.Progression of the disease is an active process leading to forming of bone matrix and heavily calcified stiff cusps by inflammato

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Protracted Clonal Trajectory of a JAK2 V617F-Positive Myeloproliferative Neoplasm Developing during Long-Term Remission from Acute Myeloid Leukemia

Although transformation of the myeloproliferative neoplasms (MPNs) to acute myeloid leukemia (AML) is well documented, development of an MPN in patients previously treated for, and in remission from, AML is exceedingly rare.A case is described in which a patient was successfully treated for AML and in whom a JAK2 V617F-positive MPN was diagnosed af

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